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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1344623
Species: Homo sapiens
RGD Object: Gene
Symbol: GSTA5
Name: glutathione S-transferase alpha 5
Acc ID: CHEBI:34247
Term: 2,6-di-tert-butyl-4-methylphenol
Definition: A member of the class of phenols that is 4-methylphenol substituted by tert-butyl groups at positions 2 and 6.
Chemical ID: MESH:D002084
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
GSTA5increases activityISOGsta5 (Rattus norvegicus)6480464CTDButylated Hydroxytoluene results in increased activity of GSTA5 proteinPMID:9328168
GSTA5multiple interactionsISOGsta5 (Rattus norvegicus)6480464CTDButylated Hydroxytoluene promotes the reaction [GSTA5 protein affects the metabolism of aflatoxin B1-2,3-oxide]; Butylated Hydroxytoluene results in increased expression of and results in increased activity of GSTA5 proteinPMID:8198522
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