Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731071
Species: Homo sapiens
RGD Object: Gene
Symbol: AHR
Name: aryl hydrocarbon receptor
Acc ID: CHEBI:34206
Term: 2,2',5,5'-tetrachlorobiphenyl
Definition: A tetrachlorobiphenyl that is biphenyl in which the hydrogens at the 2 and 5 position of each benzene ring are replaced by chlorines.
Chemical ID: MESH:C009407
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
AHRmultiple interactionsISOAhr (Mus musculus)6480464CTD2,5,2',5'-tetrachlorobiphenyl binds to and results in decreased activity of AHR protein; 2,5,2',5'-tetrachlorobiphenyl inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of and results in increased localization of AHR protein]PMID:12051995 PMID:12628580
Go Back to source page   Continue to Ontology report