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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621315
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Map1lc3b
Name: microtubule-associated protein 1 light chain 3 beta
Acc ID: CHEBI:34206
Term: 2,2',5,5'-tetrachlorobiphenyl
Definition: A tetrachlorobiphenyl that is biphenyl in which the hydrogens at the 2 and 5 position of each benzene ring are replaced by chlorines.
Chemical ID: MESH:C009407
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Map1lc3bincreases cleavageEXP 6480464CTD2,5,2',5'-tetrachlorobiphenyl results in increased cleavage of MAP1LC3B proteinPMID:29518472
Map1lc3bmultiple interactionsEXP 6480464CTD3-methyladenine inhibits the reaction [2,5,2',5'-tetrachlorobiphenyl results in increased cleavage of MAP1LC3B protein]; Sirolimus promotes the reaction [2,5,2',5'-tetrachlorobiphenyl results in increased cleavage of MAP1LC3B protein]PMID:29518472
Map1lc3bincreases cleavageISOMAP1LC3B (Homo sapiens)6480464CTD2,5,2',5'-tetrachlorobiphenyl results in increased cleavage of MAP1LC3B proteinPMID:29518472
Map1lc3bmultiple interactionsISOMAP1LC3B (Homo sapiens)6480464CTD3-methyladenine inhibits the reaction [2,5,2',5'-tetrachlorobiphenyl results in increased cleavage of MAP1LC3B protein]; Sirolimus promotes the reaction [2,5,2',5'-tetrachlorobiphenyl results in increased cleavage of MAP1LC3B protein]PMID:29518472
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