Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
2,4,5,2',4',5'-hexachlorobiphenyl promotes the reaction [Tetrachlorodibenzodioxin results in decreased expression of SREBF1 mRNA]; [Dietary Sucrose co-treated with Dietary Fats co-treated with bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in increased expression of SREBF1 mRNA; [Tetrachlorodibenzodioxin co-treated with bisphenol A co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylhexyl Phthalate] inhibits the reaction [Dietary Fats results in increased expression of SREBF1 mRNA]; Tetrachlorodibenzodioxin promotes the reaction [2,4,5,2',4',5'-hexachlorobiphenyl results in decreased expression of SREBF1 mRNA]