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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3112
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Abcc1
Name: ATP binding cassette subfamily C member 1
Acc ID: CHEBI:34172
Term: 16alpha-hydroxytestosterone
Definition: A C19-steroid that is testosterone in which the hydrogen at the 16alpha position has been replaced by a hydroxy group.
Chemical ID: MESH:C045261
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Abcc1multiple interactionsISORGD:109196480464CTD[ABCC1 gene mutant form results in increased hydroxylation of Testosterone] which results in increased chemical synthesis of 16-hydroxytestosterone

PMID:22522787
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