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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733827
Species: Mus musculus
RGD Object: Gene
Symbol: Dcxr
Name: dicarbonyl L-xylulose reductase
Acc ID: CHEBI:34055
Term: 1,2-naphthoquinone
Definition: The parent structure of the family of 1,2-naphthoquinones, in which the oxo groups of the quinone moiety are at positions 1 and 2 of the naphthalene ring. It is a metabolite of naphthalene and is found in diesel exhaust particles.
Chemical ID: MESH:C040756
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Dcxrincreases metabolic processingISODCXR (Homo sapiens)6480464CTDDCXR protein results in increased metabolism of 1,2-naphthoquinonePMID:28595002
Dcxrmultiple interactionsISODCXR (Homo sapiens)6480464CTD1,2-naphthoquinone inhibits the reaction [[[DCXR protein co-treated with NAD] results in increased reduction of Diacetyl] which results in increased chemical synthesis of Acetoin]PMID:28595002
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