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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2943
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Jun
Name: Jun proto-oncogene, AP-1 transcription factor subunit
Acc ID: CHEBI:34027
Term: 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane
Definition: A diarylmethane that has formula C14H9Cl5.
Chemical ID: MESH:C016340
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Junincreases expressionEXP 6480464CTDo,p'-DDT results in increased expression of JUN mRNAPMID:24096037
Junaffects localizationISOJUN (Homo sapiens)6480464CTDo,p'-DDT affects the localization of JUN proteinPMID:34167450
Junincreases expressionISOJun (Mus musculus)6480464CTDo,p'-DDT results in increased expression of JUN mRNAPMID:18840457 PMID:24096037
Junmultiple interactionsISOJun (Mus musculus)6480464CTDo,p'-DDT results in increased expression of and results in increased activity of JUN proteinPMID:18840457
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