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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10451
Species: Mus musculus
RGD Object: Gene
Symbol: Cyp2e1
Name: cytochrome P450, family 2, subfamily e, polypeptide 1
Acc ID: CHEBI:34026
Term: 1,1,1-Trichloro-2-(4-hydroxyphenyl)-2-(4-methoxyphenyl)ethane
Definition: A diarylmethane that has formula C15H13Cl3O2.
Chemical ID: MESH:C495657
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp2e1increases hydroxylationISOCYP2E1 (Homo sapiens)6480464CTDCYP2E1 protein results in increased hydroxylation of 1,1,1-trichloro-2-(4-hydroxyphenyl)-2-(4-methoxyphenyl)ethanePMID:9047321
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