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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 737487
Species: Homo sapiens
RGD Object: Gene
Symbol: IFNG
Name: interferon gamma
Acc ID: CHEBI:3387
Term: carbamazepine
Definition: A dibenzoazepine that is 5H-dibenzo[b,f]azepine carrying a carbamoyl substituent at the azepine nitrogen, used as an anticonvulsant.
Chemical ID: MESH:D002220
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
IFNGincreases secretionEXP 6480464CTDCarbamazepine results in increased secretion of IFNG proteinPMID:29644860
IFNGdecreases expressionISOIfng (Rattus norvegicus)6480464CTDCarbamazepine results in decreased expression of IFNGPMID:28267586
IFNGdecreases expressionISOIfng (Mus musculus)6480464CTDCarbamazepine results in decreased expression of IFNG mRNAPMID:22790970
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