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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731751
Species: Homo sapiens
RGD Object: Gene
Symbol: SLC5A5
Name: solute carrier family 5 member 5
Acc ID: CHEBI:3387
Term: carbamazepine
Definition: A dibenzoazepine that is 5H-dibenzo[b,f]azepine carrying a carbamoyl substituent at the azepine nitrogen, used as an anticonvulsant.
Chemical ID: MESH:D002220
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
SLC5A5multiple interactionsEXP 6480464CTD2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Carbamazepine promotes the reaction [Tretinoin results in increased expression of SLC5A5 protein]]; Carbamazepine promotes the reaction [Tretinoin results in increased expression of SLC5A5 mRNA]; Carbamazepine promotes the reaction [Tretinoin results in increased expression of SLC5A5 protein]; wortmannin inhibits the reaction [Carbamazepine promotes the reaction [Tretinoin results in increased expression of SLC5A5 protein]]PMID:20300827
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