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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620573
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyba
Name: cytochrome b-245 alpha chain
Acc ID: CHEBI:3387
Term: carbamazepine
Definition: A dibenzoazepine that is 5H-dibenzo[b,f]azepine carrying a carbamoyl substituent at the azepine nitrogen, used as an anticonvulsant.
Chemical ID: MESH:D002220
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cybamultiple interactionsEXP 6480464CTD[[Streptozocin co-treated with Carbamazepine] affects the susceptibility to Dietary Fats] which results in decreased expression of CYBA mRNA; [[Streptozocin co-treated with Carbamazepine] affects the susceptibility to Dietary Fats] which results in increased expression of CYBA protein; [Carbamazepine affects the susceptibility to [Dietary Fats co-treated with Streptozocin]] which results in decreased expression of CYBA mRNAPMID:35786680
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