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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620218
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Creb1
Name: cAMP responsive element binding protein 1
Acc ID: CHEBI:338412
Term: (-)-anisomycin
Definition: An antibiotic isolated from various Streptomyces species. It interferes with protein and DNA synthesis by inhibiting peptidyl transferase or the 80S ribosome system.
Chemical ID: MESH:D000841
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Creb1increases phosphorylationISOCREB1 (Homo sapiens)6480464CTDAnisomycin results in increased phosphorylation of CREB1 proteinPMID:12660819
Creb1multiple interactionsISOCREB1 (Homo sapiens)6480464CTDSB 203580 inhibits the reaction [Anisomycin results in increased phosphorylation of CREB1 protein]PMID:12660819
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