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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1344608
Species: Homo sapiens
RGD Object: Gene
Symbol: PRKACA
Name: protein kinase cAMP-activated catalytic subunit alpha
Acc ID: CHEBI:3380
Term: captopril
Definition: A L-proline derivative in which L-proline is substituted on nitrogen with a (2S)-2-methyl-3-sulfanylpropanoyl group. It is used as an anti-hypertensive ACE inhibitor drug.
Chemical ID: MESH:D002216
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PRKACAmultiple interactionsISOPrkaca (Rattus norvegicus)6480464CTDCaptopril inhibits the reaction [Pregabalin results in decreased expression of PRKACA protein]PMID:31629013
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