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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 11429
Species: Mus musculus
RGD Object: Gene
Symbol: Tnf
Name: tumor necrosis factor
Acc ID: CHEBI:33787
Term: beryllium dihydride
Definition: A beryllium hydride that has formula BeH2.
Chemical ID: MESH:D001608
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tnfincreases expressionISOTNF (Homo sapiens)6480464CTDBeryllium results in increased expression of TNF mRNAPMID:8629860
Tnfincreases response to substanceISOTNF (Homo sapiens)6480464CTDTNF promoter polymorphism results in increased susceptibility to BerylliumPMID:15127972
Tnfincreases secretionISOTNF (Homo sapiens)6480464CTDBeryllium results in increased secretion of TNF proteinPMID:12449171
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