GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | ABCA1 | increases expression | ISO | Abca1 (Mus musculus) | 6480464 | CTD | Capsaicin results in increased expression of ABCA1 protein | PMID:21908651 | ABCA1 | increases response to substance | ISO | Abca1 (Mus musculus) | 6480464 | CTD | ABCA1 results in increased susceptibility to Capsaicin | PMID:21908651 | ABCA1 | multiple interactions | ISO | Abca1 (Mus musculus) | 6480464 | CTD | 1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid inhibits the reaction [Capsaicin results in increased expression of ABCA1 protein]; [Capsaicin results in increased expression of ABCA1 protein] which results in decreased uptake of Cholesterol; [Capsaicin results in increased expression of ABCA1 protein] which results in increased secretion of Cholesterol; APOE affects the reaction [Capsaicin results in increased expression of ABCA1 protein]; Cyclosporine affects the reaction [Capsaicin results in increased expression of ABCA1 protein]; KT 5720 inhibits the reaction [Capsaicin results in increased expression of ABCA1 protein]; TRPV1 gene mutant form inhibits the reaction [Capsaicin results in increased expression of ABCA1 protein] | PMID:21908651 | | ||||||||||||||||||||||
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