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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732775
Species: Homo sapiens
RGD Object: Gene
Symbol: ALOX5
Name: arachidonate 5-lipoxygenase
Acc ID: CHEBI:3374
Term: capsaicin
Definition: A capsaicinoid that has formula C18H27NO3.
Chemical ID: MESH:D002211
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ALOX5decreases activityISOAlox5 (Rattus norvegicus)6480464CTDCapsaicin results in decreased activity of ALOX5 proteinPMID:16956363
ALOX5multiple interactionsISOAlox5 (Rattus norvegicus)6480464CTD[Capsaicin co-treated with Curcumin] results in decreased activity of ALOX5 proteinPMID:16956363
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