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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 70499
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Birc5
Name: baculoviral IAP repeat-containing 5
Acc ID: CHEBI:3374
Term: capsaicin
Definition: A capsaicinoid that has formula C18H27NO3.
Chemical ID: MESH:D002211
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Birc5decreases expressionISOBIRC5 (Homo sapiens)6480464CTDCapsaicin results in decreased expression of BIRC5; Capsaicin results in decreased expression of BIRC5 proteinPMID:17505005 PMID:19002586 PMID:19939880
Birc5multiple interactionsISOBIRC5 (Homo sapiens)6480464CTDbenzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Capsaicin results in decreased expression of BIRC5 protein]; BIRC5 results in decreased activity of [Capsaicin co-treated with TNFSF10 protein]PMID:19939880
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