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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619831
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Fas
Name: Fas cell surface death receptor
Acc ID: CHEBI:3374
Term: capsaicin
Definition: A capsaicinoid that has formula C18H27NO3.
Chemical ID: MESH:D002211
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fasincreases expressionEXP 6480464CTDCapsaicin results in increased expression of FAS proteinPMID:22150557
Fasmultiple interactionsEXP 6480464CTD[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of FAS protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of FAS protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of FAS protein]PMID:22150557
Fasaffects expressionISOFAS (Homo sapiens)6480464CTDCapsaicin affects the expression of FAS mRNAPMID:21310942
Fasincreases expressionISOFAS (Homo sapiens)6480464CTDCapsaicin results in increased expression of FAS mRNA; Capsaicin results in increased expression of FAS proteinPMID:19502594
Fasmultiple interactionsISOFAS (Homo sapiens)6480464CTDCapsaicin promotes the reaction [resveratrol results in increased expression of FAS protein]PMID:19846903
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