GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | LRP1 | decreases expression | ISO | Lrp1 (Mus musculus) | 6480464 | CTD | Capsaicin results in decreased expression of LRP1 protein | PMID:21908651 | LRP1 | decreases response to substance | ISO | Lrp1 (Mus musculus) | 6480464 | CTD | LRP1 results in decreased susceptibility to Capsaicin | PMID:21908651 | LRP1 | multiple interactions | ISO | Lrp1 (Mus musculus) | 6480464 | CTD | 1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid inhibits the reaction [Capsaicin results in decreased expression of LRP1 protein]; [Capsaicin results in decreased expression of LRP1 protein] which results in decreased uptake of Cholesterol; [Capsaicin results in decreased expression of LRP1 protein] which results in increased secretion of Cholesterol; APOE affects the reaction [Capsaicin results in decreased expression of LRP1 protein]; Cyclosporine inhibits the reaction [Capsaicin results in decreased expression of LRP1 protein]; KT 5720 inhibits the reaction [Capsaicin results in decreased expression of LRP1 protein]; TRPV1 gene mutant form inhibits the reaction [Capsaicin results in decreased expression of LRP1 protein] | PMID:21908651 | | ||||||||||||||||||||||
| Go Back to source page | Continue to Ontology report |