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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732816
Species: Homo sapiens
RGD Object: Gene
Symbol: SLC12A2
Name: solute carrier family 12 member 2
Acc ID: CHEBI:33322
Term: rubidium atom
Definition: An alkali metal atom that has formula Rb.
Chemical ID: MESH:D012413
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
SLC12A2increases uptakeEXP 6480464CTDSLC12A2 protein results in increased uptake of RubidiumPMID:29959396
SLC12A2multiple interactionsEXP 6480464CTDazosemide inhibits the reaction [SLC12A2 protein results in increased uptake of Rubidium]; Bumetanide inhibits the reaction [SLC12A2 protein results in increased uptake of Rubidium]; Ethacrynic Acid inhibits the reaction [SLC12A2 protein results in increased uptake of Rubidium]; Furosemide inhibits the reaction [SLC12A2 protein results in increased uptake of Rubidium]; piretanide inhibits the reaction [SLC12A2 protein results in increased uptake of Rubidium]; Ticrynafen inhibits the reaction [SLC12A2 protein results in increased uptake of Rubidium]; Torsemide inhibits the reaction [SLC12A2 protein results in increased uptake of Rubidium]PMID:29959396
SLC12A2multiple interactionsISOSlc12a2 (Rattus norvegicus)6480464CTD2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Phenylephrine promotes the reaction [SLC12A2 protein results in increased uptake of Rubidium]]; [calyculin A results in increased phosphorylation of SLC12A2 protein] inhibits the reaction [Bumetanide inhibits the reaction [SLC12A2 protein results in increased uptake of Rubidium]]; Bumetanide inhibits the reaction [SLC12A2 protein results in increased uptake of Rubidium]; Phenylephrine promotes the reaction [SLC12A2 protein results in increased uptake of Rubidium]PMID:14630635
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