Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731002
Species: Homo sapiens
RGD Object: Gene
Symbol: CASP3
Name: caspase 3
Acc ID: CHEBI:3330
Term: Calpeptin
Definition: An amino acid amide that has formula C20H30N2O4.
Chemical ID: MESH:C071482
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CASP3multiple interactionsEXP 6480464CTDcalpeptin inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]PMID:35525317
CASP3multiple interactionsISOCasp3 (Mus musculus)6480464CTDcalpeptin inhibits the reaction [[lactacystin results in increased activity of CASP3 protein] which results in increased cleavage of SPTAN1 protein]; calpeptin inhibits the reaction [Cadmium results in increased cleavage of CASP3 protein]PMID:21683092 PMID:29111403
CASP3multiple interactionsISOCasp3 (Rattus norvegicus)6480464CTDcalpeptin inhibits the reaction [Paraquat results in increased cleavage of CASP3 protein]; calpeptin inhibits the reaction [Propofol results in increased cleavage of CASP3 protein]PMID:25947082 PMID:36640868
Go Back to source page   Continue to Ontology report