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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69057
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nr1i2
Name: nuclear receptor subfamily 1, group I, member 2
Acc ID: CHEBI:33275
Term: beta-tocotrienol
Definition: A tocotrienol that is chroman-6-ol substituted by methyl groups at positions 2, 5 and 8 and a farnesyl chain at position 2. It has been isolated from various cultivars of wheat.
Chemical ID: MESH:C082089
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nr1i2multiple interactionsISORGD:691056480464CTDtocotrienol, beta binds to and results in increased activity of NR1I2 protein, tocotrienol, beta inhibits the reaction [NR1I2 protein binds to NCOR1 protein]

PMID:15269186
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