GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | App | multiple interactions | EXP | | 6480464 | CTD | Vitamin E inhibits the reaction [Aluminum results in increased cleavage of APP protein] | PMID:12039845 | App | decreases expression | ISO | APP (Homo sapiens) | 6480464 | CTD | Vitamin E results in decreased expression of APP mRNA | PMID:19244175 | App | multiple interactions | ISO | App (Rattus norvegicus) | 6480464 | CTD | Vitamin E inhibits the reaction [APP protein modified form promotes the reaction [[IFNG protein co-treated with Lipopolysaccharides] results in increased expression of NOS2 protein]]; Vitamin E inhibits the reaction [APP protein results in increased activity of CASP3] | PMID:12117551 PMID:15223066 | |
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