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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735861
Species: Homo sapiens
RGD Object: Gene
Symbol: THY1
Name: Thy-1 cell surface antigen
Acc ID: CHEBI:33217
Term: 3,3',5,5'-tetrabromobisphenol A
Definition: A bromobisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups and the phenyl rings are substituted by bromo groups at positions 2, 2', 6 and 6'. It is a brominated flame retardant.
Chemical ID: MESH:C020806
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
THY1decreases expressionEXP 6480464CTDtetrabromobisphenol A results in decreased expression of THY1 mRNA; tetrabromobisphenol A results in decreased expression of THY1 proteinPMID:28329833
THY1multiple interactionsEXP 6480464CTD[tetrabromobisphenol A results in increased expression of MIR103A1] which results in decreased expression of THY1 mRNA; [tetrabromobisphenol A results in increased expression of MIR103A1] which results in decreased expression of THY1 proteinPMID:28329833
THY1decreases expressionISOThy1 (Mus musculus)6480464CTDtetrabromobisphenol A results in decreased expression of THY1 mRNA; tetrabromobisphenol A results in decreased expression of THY1 proteinPMID:28329833 PMID:30496566
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