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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732227
Species: Homo sapiens
RGD Object: Gene
Symbol: NR3C1
Name: nuclear receptor subfamily 3 group C member 1
Acc ID: CHEBI:33217
Term: 3,3',5,5'-tetrabromobisphenol A
Definition: A bromobisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups and the phenyl rings are substituted by bromo groups at positions 2, 2', 6 and 6'. It is a brominated flame retardant.
Chemical ID: MESH:C020806
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
NR3C1multiple interactionsEXP 6480464CTDtetrabromobisphenol A inhibits the reaction [Dexamethasone results in increased activity of NR3C1 protein]PMID:25576683
NR3C1affects expressionISONr3c1 (Rattus norvegicus)6480464CTDtetrabromobisphenol A affects the expression of NR3C1 mRNAPMID:26988606
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