Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2192
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bax
Name: BCL2 associated X, apoptosis regulator
Acc ID: CHEBI:33217
Term: 3,3',5,5'-tetrabromobisphenol A
Definition: A bromobisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups and the phenyl rings are substituted by bromo groups at positions 2, 2', 6 and 6'. It is a brominated flame retardant.
Chemical ID: MESH:C020806
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Baxincreases expressionISOBax (Mus musculus)6480464CTDtetrabromobisphenol A results in increased expression of BAX mRNAPMID:22677475
Baxincreases expressionISOBAX (Homo sapiens)6480464CTDtetrabromobisphenol A results in increased expression of BAX mRNA; tetrabromobisphenol A results in increased expression of BAX proteinPMID:30951941
Go Back to source page   Continue to Ontology report