GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | ACE | increases expression | EXP | | 6480464 | CTD | bisphenol A results in increased expression of ACE mRNA | PMID:27622962 | ACE | decreases activity | ISO | Ace (Rattus norvegicus) | 6480464 | CTD | bisphenol A results in decreased activity of ACE protein | PMID:32153214 | ACE | decreases expression | ISO | Ace (Rattus norvegicus) | 6480464 | CTD | bisphenol A results in decreased expression of ACE mRNA | PMID:25181051 | ACE | decreases methylation | ISO | Ace (Mus musculus) | 6480464 | CTD | bisphenol A results in decreased methylation of ACE promoter | PMID:27312807 | ACE | increases activity | ISO | Ace (Rattus norvegicus) | 6480464 | CTD | bisphenol A results in increased activity of ACE protein | PMID:32172062 PMID:32810514 | ACE | increases expression | ISO | Ace (Mus musculus) | 6480464 | CTD | bisphenol A results in increased expression of ACE mRNA | PMID:37392660 | ACE | increases expression | ISO | Ace (Rattus norvegicus) | 6480464 | CTD | bisphenol A results in increased expression of ACE mRNA; bisphenol A results in increased expression of ACE protein | PMID:38027817 | ACE | multiple interactions | ISO | Ace (Rattus norvegicus) | 6480464 | CTD | [bisphenol A co-treated with Fructose] results in increased expression of ACE mRNA; [NG-Nitroarginine Methyl Ester co-treated with bisphenol A] results in increased activity of ACE protein; bisphenol A promotes the reaction [NG-Nitroarginine Methyl Ester results in increased activity of ACE protein]; Lycopene inhibits the reaction [bisphenol A results in decreased activity of ACE protein]; naringin inhibits the reaction [[NG-Nitroarginine Methyl Ester co-treated with bisphenol A] results in increased activity of ACE protein]; naringin inhibits the reaction [bisphenol A promotes the reaction [NG-Nitroarginine Methyl Ester results in increased activity of ACE protein]]; naringin inhibits the reaction [bisphenol A results in increased activity of ACE protein]; naringin inhibits the reaction [NG-Nitroarginine Methyl Ester promotes the reaction [bisphenol A results in increased activity of ACE protein]]; NG-Nitroarginine Methyl Ester promotes the reaction [bisphenol A results in increased activity of ACE protein] | PMID:27622962 PMID:32153214 PMID:32172062 PMID:32810514 | | ||||||||||||||||||||||
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