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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736944
Species: Homo sapiens
RGD Object: Gene
Symbol: SYT1
Name: synaptotagmin 1
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
SYT1decreases expressionISOSyt1 (Mus musculus)6480464CTDbisphenol A results in decreased expression of SYT1 mRNAPMID:32156529
SYT1decreases methylationISOSyt1 (Mus musculus)6480464CTDbisphenol A results in decreased methylation of SYT1 promoterPMID:27312807
SYT1increases expressionISOSyt1 (Rattus norvegicus)6480464CTDbisphenol A results in increased expression of SYT1 mRNAPMID:25181051
SYT1increases methylationISOSyt1 (Rattus norvegicus)6480464CTDbisphenol A results in increased methylation of SYT1 genePMID:28505145
SYT1multiple interactionsISOSyt1 (Rattus norvegicus)6480464CTD[bisphenol A co-treated with Testosterone] results in decreased expression of SYT1 mRNAPMID:26496021
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