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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736832
Species: Homo sapiens
RGD Object: Gene
Symbol: EGF
Name: epidermal growth factor
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
EGFdecreases expressionEXP 6480464CTDbisphenol A results in decreased expression of EGF mRNAPMID:31230753
EGFincreases expressionEXP 6480464CTDbisphenol A results in increased expression of EGF mRNAPMID:30022450
EGFincreases secretionEXP 6480464CTDbisphenol A results in increased secretion of EGF proteinPMID:30022450
EGFdecreases expressionISOEgf (Rattus norvegicus)6480464CTDbisphenol A results in decreased expression of EGF mRNAPMID:25181051
EGFincreases expressionISOEgf (Mus musculus)6480464CTDbisphenol A results in increased expression of EGF mRNAPMID:11011959 PMID:32353937
EGFincreases expressionISOEgf (Rattus norvegicus)6480464CTDbisphenol A results in increased expression of EGF mRNAPMID:31771501
EGFincreases methylationISOEgf (Rattus norvegicus)6480464CTDbisphenol A results in increased methylation of EGF genePMID:28505145
EGFmultiple interactionsISOEgf (Rattus norvegicus)6480464CTD[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of EGF mRNAPMID:25607892
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