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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736208
Species: Homo sapiens
RGD Object: Gene
Symbol: CEBPB
Name: CCAAT enhancer binding protein beta
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CEBPBaffects expressionEXP 6480464CTDbisphenol A affects the expression of CEBPB mRNAPMID:30903817
CEBPBdecreases expressionEXP 6480464CTDbisphenol A results in decreased expression of CEBPB mRNAPMID:32387340
CEBPBincreases expressionEXP 6480464CTDbisphenol A analog results in increased expression of CEBPB mRNA; bisphenol A results in increased expression of CEBPB mRNA; bisphenol A results in increased expression of CEBPB proteinPMID:24418828 PMID:29275510 PMID:30206973 PMID:32387340
CEBPBmultiple interactionsEXP 6480464CTD[Vitamin D co-treated with bisphenol A co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of CEBPB mRNAPMID:33836827
CEBPBdecreases expressionISOCebpb (Mus musculus)6480464CTDbisphenol A results in decreased expression of CEBPB mRNAPMID:26063408 PMID:35598803
CEBPBincreases expressionISOCebpb (Mus musculus)6480464CTDbisphenol A results in increased expression of CEBPB mRNAPMID:18359623
CEBPBincreases expressionISOCebpb (Rattus norvegicus)6480464CTDbisphenol A results in increased expression of CEBPB mRNAPMID:25181051 PMID:32145629 PMID:34947998
CEBPBmultiple interactionsISOCebpb (Mus musculus)6480464CTD[Tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylhexyl Phthalate co-treated with bisphenol A] results in increased expression of CEBPB mRNA; bisphenol A promotes the reaction [[NR3C1 protein co-treated with CEBPB protein] results in increased expression of FABP4 mRNA]; bisphenol A promotes the reaction [CEBPB protein results in increased expression of FABP4 mRNA]PMID:25068083 PMID:28433925
CEBPBmultiple interactionsISOCebpb (Rattus norvegicus)6480464CTDbisphenol A inhibits the reaction [CEBPB protein binds to CPT1A promoter]PMID:25748669
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