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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736136
Species: Homo sapiens
RGD Object: Gene
Symbol: ASS1
Name: argininosuccinate synthase 1
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ASS1affects expressionEXP 6480464CTDbisphenol A affects the expression of ASS1 mRNAPMID:30903817
ASS1decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of ASS1 proteinPMID:34186270
ASS1increases expressionEXP 6480464CTDbisphenol A analog results in increased expression of ASS1 mRNA; bisphenol A results in increased expression of ASS1 mRNA; bisphenol A results in increased expression of ASS1 proteinPMID:29275510 PMID:32387340 PMID:37567409
ASS1affects expressionISOAss1 (Rattus norvegicus)6480464CTDbisphenol A affects the expression of ASS1 mRNAPMID:25181051 PMID:30903817
ASS1decreases expressionISOAss1 (Rattus norvegicus)6480464CTDbisphenol A results in decreased expression of ASS1 mRNA; bisphenol A results in decreased expression of ASS1 proteinPMID:30816183 PMID:32145629 PMID:32528016 PMID:34947998
ASS1increases expressionISOAss1 (Mus musculus)6480464CTDbisphenol A results in increased expression of ASS1 mRNAPMID:32156529
ASS1multiple interactionsISOAss1 (Mus musculus)6480464CTD[bisphenol A co-treated with Tretinoin] results in decreased expression of ASS1 mRNAPMID:30951980
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