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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735898
Species: Mus musculus
RGD Object: Gene
Symbol: Gls2
Name: glutaminase 2 (liver, mitochondrial)
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gls2decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of GLS2 mRNAPMID:35598803
Gls2increases expressionEXP 6480464CTDbisphenol A results in increased expression of GLS2 mRNAPMID:33221593
Gls2multiple interactionsEXP 6480464CTD[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in decreased expression of GLS2 mRNAPMID:37364641
Gls2affects expressionISOGls2 (Rattus norvegicus)6480464CTDbisphenol A affects the expression of GLS2 mRNAPMID:30903817
Gls2decreases expressionISOGls2 (Rattus norvegicus)6480464CTDbisphenol A results in decreased expression of GLS2 mRNAPMID:30816183 PMID:32145629 PMID:32528016
Gls2increases expressionISOGls2 (Rattus norvegicus)6480464CTDbisphenol A results in increased expression of GLS2 mRNAPMID:25181051
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