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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735865
Species: Homo sapiens
RGD Object: Gene
Symbol: ANXA3
Name: annexin A3
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ANXA3decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of ANXA3 mRNA; bisphenol A results in decreased expression of ANXA3 proteinPMID:29275510 PMID:33376534
ANXA3increases expressionEXP 6480464CTDbisphenol A results in increased expression of ANXA3 proteinPMID:37567409
ANXA3multiple interactionsEXP 6480464CTD[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of ANXA3 mRNA; [Phenolsulfonphthalein deficiency co-treated with bisphenol A deficiency] results in increased expression of ANXA3 proteinPMID:28628672 PMID:31629898
ANXA3affects expressionISOAnxa3 (Rattus norvegicus)6480464CTDbisphenol A affects the expression of ANXA3 mRNAPMID:25181051
ANXA3decreases expressionISOAnxa3 (Rattus norvegicus)6480464CTDbisphenol A results in decreased expression of ANXA3 mRNAPMID:34947998
ANXA3increases expressionISOAnxa3 (Rattus norvegicus)6480464CTDbisphenol A results in increased expression of ANXA3 mRNAPMID:30816183 PMID:32145629 PMID:32528016
ANXA3increases expressionISOAnxa3 (Mus musculus)6480464CTDbisphenol A results in increased expression of ANXA3 mRNAPMID:30951980
ANXA3increases methylationISOAnxa3 (Rattus norvegicus)6480464CTDbisphenol A results in increased methylation of ANXA3 genePMID:28505145
ANXA3multiple interactionsISOAnxa3 (Rattus norvegicus)6480464CTD[bisphenol A co-treated with Testosterone] results in increased expression of ANXA3 mRNAPMID:26496021
ANXA3multiple interactionsISOAnxa3 (Mus musculus)6480464CTD[bisphenol A co-treated with Tretinoin] results in decreased expression of ANXA3 mRNAPMID:30951980
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