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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735810
Species: Mus musculus
RGD Object: Gene
Symbol: Nr2c2
Name: nuclear receptor subfamily 2, group C, member 2
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nr2c2affects methylationEXP 6480464CTDbisphenol A affects the methylation of NR2C2 promoterPMID:27334623
Nr2c2increases expressionEXP 6480464CTDbisphenol A results in increased expression of NR2C2 mRNAPMID:26063408
Nr2c2affects expressionISONr2c2 (Rattus norvegicus)6480464CTDbisphenol A affects the expression of NR2C2 mRNAPMID:25181051 PMID:32145629
Nr2c2increases expressionISONr2c2 (Rattus norvegicus)6480464CTDbisphenol A results in increased expression of NR2C2 mRNAPMID:29097150 PMID:33296240
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