GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Hk2 | affects expression | ISO | Hk2 (Rattus norvegicus) | 6480464 | CTD | bisphenol A affects the expression of HK2 mRNA | PMID:25181051 | Hk2 | affects expression | ISO | HK2 (Homo sapiens) | 6480464 | CTD | bisphenol A affects the expression of HK2 mRNA | PMID:30903817 | Hk2 | decreases expression | ISO | Hk2 (Rattus norvegicus) | 6480464 | CTD | bisphenol A results in decreased expression of HK2 mRNA | PMID:30816183 PMID:32528016 PMID:34947998 | Hk2 | increases expression | ISO | HK2 (Homo sapiens) | 6480464 | CTD | bisphenol A results in increased expression of HK2 protein | PMID:34186270 | Hk2 | increases methylation | ISO | Hk2 (Rattus norvegicus) | 6480464 | CTD | bisphenol A results in increased methylation of HK2 gene | PMID:28505145 | Hk2 | multiple interactions | ISO | HK2 (Homo sapiens) | 6480464 | CTD | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of HK2 mRNA; [naringenin co-treated with bisphenol A] results in increased expression of HK2 mRNA; [naringenin metabolite co-treated with bisphenol A] results in increased expression of HK2 mRNA | PMID:28628672 PMID:36235125 | |
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