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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735560
Species: Homo sapiens
RGD Object: Gene
Symbol: PFKFB3
Name: 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PFKFB3affects expressionEXP 6480464CTDbisphenol A affects the expression of PFKFB3 mRNAPMID:30903817
PFKFB3multiple interactionsEXP 6480464CTD[bisphenol A co-treated with Fulvestrant] results in increased methylation of PFKFB3 genePMID:31601247
PFKFB3decreases expressionISOPfkfb3 (Rattus norvegicus)6480464CTDbisphenol A results in decreased expression of PFKFB3 mRNAPMID:25181051
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