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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735540
Species: Mus musculus
RGD Object: Gene
Symbol: Axin2
Name: axin 2
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Axin2decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of AXIN2 mRNAPMID:33221593
Axin2decreases methylationEXP 6480464CTDbisphenol A results in decreased methylation of AXIN2 promoterPMID:27312807
Axin2increases expressionEXP 6480464CTDbisphenol A results in increased expression of AXIN2 mRNAPMID:32156529
Axin2decreases expressionISOAXIN2 (Homo sapiens)6480464CTDbisphenol A results in decreased expression of AXIN2 mRNAPMID:27685785
Axin2decreases expressionISOAxin2 (Rattus norvegicus)6480464CTDbisphenol A results in decreased expression of AXIN2 mRNAPMID:25181051 PMID:30816183 PMID:32528016 PMID:34947998
Axin2decreases methylationISOAXIN2 (Homo sapiens)6480464CTDbisphenol A results in decreased methylation of AXIN2 genePMID:31601247
Axin2increases expressionISOAxin2 (Rattus norvegicus)6480464CTDbisphenol A results in increased expression of AXIN2 mRNAPMID:32145629
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