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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735125
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pde8a
Name: phosphodiesterase 8A
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pde8adecreases expressionEXP 6480464CTDbisphenol A results in decreased expression of PDE8A mRNAPMID:25181051 PMID:32145629
Pde8amultiple interactionsEXP 6480464CTD[bisphenol A co-treated with Testosterone] results in increased expression of PDE8A mRNAPMID:26496021
Pde8aaffects methylationISOPDE8A (Homo sapiens)6480464CTDbisphenol A affects the methylation of PDE8A genePMID:33391824
Pde8adecreases expressionISOPde8a (Mus musculus)6480464CTDbisphenol A results in decreased expression of PDE8A mRNAPMID:33221593
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