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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735099
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hp1bp3
Name: heterochromatin protein 1, binding protein 3
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hp1bp3increases expressionEXP 6480464CTDbisphenol A results in increased expression of HP1BP3 mRNAPMID:25181051 PMID:30816183 PMID:32528016
Hp1bp3multiple interactionsEXP 6480464CTD[bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of HP1BP3 mRNAPMID:36041667
Hp1bp3decreases methylationISOHp1bp3 (Mus musculus)6480464CTDbisphenol A results in decreased methylation of HP1BP3 promoterPMID:27312807
Hp1bp3increases expressionISOHp1bp3 (Mus musculus)6480464CTDbisphenol A results in increased expression of HP1BP3 mRNAPMID:26063408
Hp1bp3increases expressionISOHP1BP3 (Homo sapiens)6480464CTDbisphenol A results in increased expression of HP1BP3 proteinPMID:37567409
Hp1bp3increases methylationISOHp1bp3 (Mus musculus)6480464CTDbisphenol A results in increased methylation of HP1BP3 promoterPMID:27312807
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