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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 734152
Species: Mus musculus
RGD Object: Gene
Symbol: Snap25
Name: synaptosomal-associated protein 25
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Snap25affects expressionEXP 6480464CTDbisphenol A affects the expression of SNAP25 mRNAPMID:29161229
Snap25decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of SNAP25 mRNAPMID:32156529
Snap25affects methylationISOSNAP25 (Homo sapiens)6480464CTDbisphenol A affects the methylation of SNAP25 genePMID:33391824
Snap25decreases expressionISOSnap25 (Rattus norvegicus)6480464CTDbisphenol A results in decreased expression of SNAP25 mRNAPMID:22946080 PMID:25181051 PMID:30816183 PMID:34947998 PMID:36803626
Snap25decreases methylationISOSNAP25 (Homo sapiens)6480464CTDbisphenol A results in decreased methylation of SNAP25 genePMID:31601247
Snap25multiple interactionsISOSnap25 (Rattus norvegicus)6480464CTD[bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of SNAP25 mRNAPMID:36041667
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