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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733884
Species: Homo sapiens
RGD Object: Gene
Symbol: AMPH
Name: amphiphysin
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
AMPHincreases methylationEXP 6480464CTDbisphenol A results in increased methylation of AMPH genePMID:31601247
AMPHmultiple interactionsEXP 6480464CTD[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of AMPH mRNAPMID:28628672
AMPHdecreases expressionISOAmph (Rattus norvegicus)6480464CTDbisphenol A results in decreased expression of AMPH mRNAPMID:25181051 PMID:30816183 PMID:34947998
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