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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733443
Species: Mus musculus
RGD Object: Gene
Symbol: Ccnd3
Name: cyclin D3
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ccnd3increases expressionEXP 6480464CTDbisphenol A results in increased expression of CCND3 mRNAPMID:33221593
Ccnd3affects expressionISOCCND3 (Homo sapiens)6480464CTDbisphenol A affects the expression of CCND3 mRNAPMID:21826169
Ccnd3increases expressionISOCCND3 (Homo sapiens)6480464CTDbisphenol A results in increased expression of CCND3 proteinPMID:23222814
Ccnd3multiple interactionsISOCcnd3 (Rattus norvegicus)6480464CTD[bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of CCND3 mRNAPMID:36041667
Ccnd3multiple interactionsISOCCND3 (Homo sapiens)6480464CTD[bisphenol A co-treated with Fulvestrant] results in decreased methylation of CCND3 gene; Curcumin inhibits the reaction [bisphenol A results in increased expression of CCND3 protein]PMID:23222814 PMID:31601247
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