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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733169
Species: Mus musculus
RGD Object: Gene
Symbol: Fmo5
Name: flavin containing monooxygenase 5
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fmo5affects methylationEXP 6480464CTDbisphenol A affects the methylation of FMO5 promoterPMID:27334623
Fmo5multiple interactionsEXP 6480464CTD[Tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylhexyl Phthalate co-treated with bisphenol A] results in increased expression of FMO5 mRNAPMID:28433925
Fmo5affects expressionISOFmo5 (Rattus norvegicus)6480464CTDbisphenol A affects the expression of FMO5 mRNAPMID:30903817
Fmo5affects expressionISOFMO5 (Homo sapiens)6480464CTDbisphenol A affects the expression of FMO5 mRNAPMID:30903817
Fmo5decreases expressionISOFmo5 (Rattus norvegicus)6480464CTDbisphenol A results in decreased expression of FMO5 mRNA; bisphenol A results in decreased expression of FMO5 proteinPMID:25181051 PMID:32145629
Fmo5multiple interactionsISOFmo5 (Rattus norvegicus)6480464CTD[bisphenol A co-treated with Estradiol] results in increased expression of FMO5 mRNAPMID:26496021
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