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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733138
Species: Homo sapiens
RGD Object: Gene
Symbol: CRHR2
Name: corticotropin releasing hormone receptor 2
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CRHR2decreases expressionISOCrhr2 (Rattus norvegicus)6480464CTDbisphenol A results in decreased expression of CRHR2 mRNAPMID:25181051
CRHR2increases methylationISOCrhr2 (Rattus norvegicus)6480464CTDbisphenol A results in increased methylation of CRHR2 genePMID:28505145
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