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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732883
Species: Homo sapiens
RGD Object: Gene
Symbol: YBX1
Name: Y-box binding protein 1
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
YBX1decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of YBX1 proteinPMID:31675489
YBX1decreases methylationEXP 6480464CTDbisphenol A results in decreased methylation of YBX1 genePMID:31601247
YBX1multiple interactionsEXP 6480464CTD[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of YBX1 mRNAPMID:28628672
YBX1affects methylationISOYbx1 (Mus musculus)6480464CTDbisphenol A affects the methylation of YBX1 promoterPMID:27334623
YBX1decreases expressionISOYbx1 (Mus musculus)6480464CTDbisphenol A results in decreased expression of YBX1 mRNAPMID:33221593
YBX1decreases methylationISOYbx1 (Mus musculus)6480464CTDbisphenol A results in decreased methylation of YBX1 promoterPMID:27312807
YBX1increases expressionISOYbx1 (Rattus norvegicus)6480464CTDbisphenol A results in increased expression of YBX1 mRNAPMID:25181051
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