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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732816
Species: Homo sapiens
RGD Object: Gene
Symbol: SLC12A2
Name: solute carrier family 12 member 2
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
SLC12A2decreases expressionISOSlc12a2 (Rattus norvegicus)6480464CTDbisphenol A results in decreased expression of SLC12A2 mRNAPMID:25181051
SLC12A2increases expressionISOSlc12a2 (Rattus norvegicus)6480464CTDbisphenol A results in increased expression of SLC12A2 mRNAPMID:30816183
SLC12A2increases expressionISOSlc12a2 (Mus musculus)6480464CTDbisphenol A results in increased expression of SLC12A2 mRNAPMID:33221593
SLC12A2multiple interactionsISOSlc12a2 (Rattus norvegicus)6480464CTD[bisphenol A co-treated with Estradiol] results in increased expression of SLC12A2 mRNAPMID:26496021
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