GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | NFKBIB | decreases methylation | EXP | | 6480464 | CTD | bisphenol A results in decreased methylation of NFKBIB gene | PMID:31601247 | NFKBIB | increases expression | EXP | | 6480464 | CTD | bisphenol A results in increased expression of NFKBIB mRNA | PMID:19371625 | NFKBIB | multiple interactions | EXP | | 6480464 | CTD | [bisphenol A binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to NFKBIB protein modified form]; bisphenol A inhibits the reaction [ESR1 protein binds to NFKBIB protein]; NFKBIB protein affects the reaction [bisphenol A results in decreased expression of APOA1 mRNA] | PMID:28751236 PMID:29389661 PMID:31842455 | NFKBIB | decreases expression | ISO | Nfkbib (Rattus norvegicus) | 6480464 | CTD | bisphenol A results in decreased expression of NFKBIB mRNA | PMID:30816183 PMID:32528016 | NFKBIB | increases expression | ISO | Nfkbib (Rattus norvegicus) | 6480464 | CTD | bisphenol A results in increased expression of NFKBIB mRNA | PMID:25181051 | |
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