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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732492
Species: Mus musculus
RGD Object: Gene
Symbol: Gna12
Name: guanine nucleotide binding protein, alpha 12
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gna12increases expressionEXP 6480464CTDbisphenol A results in increased expression of GNA12 mRNAPMID:20826375
Gna12increases methylationEXP 6480464CTDbisphenol A results in increased methylation of GNA12 promoterPMID:27312807
Gna12affects expressionISOGna12 (Rattus norvegicus)6480464CTDbisphenol A affects the expression of GNA12 mRNAPMID:25181051
Gna12increases methylationISOGna12 (Rattus norvegicus)6480464CTDbisphenol A results in increased methylation of GNA12 genePMID:28505145
Gna12multiple interactionsISOGNA12 (Homo sapiens)6480464CTDbisphenol A promotes the reaction [GNA12 protein binds to ESR1 protein]PMID:27156127
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