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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732446
Species: Homo sapiens
RGD Object: Gene
Symbol: GRIA2
Name: glutamate ionotropic receptor AMPA type subunit 2
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
GRIA2decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of GRIA2 mRNAPMID:30953815
GRIA2decreases methylationEXP 6480464CTDbisphenol A results in decreased methylation of GRIA2 genePMID:31601247
GRIA2decreases expressionISOGria2 (Rattus norvegicus)6480464CTDbisphenol A results in decreased expression of GRIA2 mRNAPMID:22504913 PMID:25181051
GRIA2decreases expressionISOGria2 (Mus musculus)6480464CTDbisphenol A results in decreased expression of GRIA2 mRNAPMID:32156529
GRIA2multiple interactionsISOGria2 (Rattus norvegicus)6480464CTD[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of GRIA2 mRNAPMID:25607892
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