Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732397
Species: Mus musculus
RGD Object: Gene
Symbol: Jup
Name: junction plakoglobin
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Jupaffects methylationEXP 6480464CTDbisphenol A affects the methylation of JUP promoterPMID:27334623
Jupincreases expressionEXP 6480464CTDbisphenol A results in increased expression of JUP mRNAPMID:32156529
Jupdecreases expressionISOJup (Rattus norvegicus)6480464CTDbisphenol A results in decreased expression of JUP mRNAPMID:30816183 PMID:32145629 PMID:34947998
Jupdecreases expressionISOJUP (Homo sapiens)6480464CTDbisphenol A results in decreased expression of JUP mRNAPMID:16474171
Jupdecreases methylationISOJUP (Homo sapiens)6480464CTDbisphenol A results in decreased methylation of JUP genePMID:31601247
Jupincreases expressionISOJup (Rattus norvegicus)6480464CTDbisphenol A results in increased expression of JUP mRNAPMID:25181051
Jupincreases expressionISOJUP (Homo sapiens)6480464CTDbisphenol A results in increased expression of JUP mRNA; bisphenol A results in increased expression of JUP proteinPMID:27685785 PMID:37567409
Jupmultiple interactionsISOJup (Rattus norvegicus)6480464CTD[Fructose co-treated with bisphenol A] results in increased expression of JUP proteinPMID:26930160
Jupmultiple interactionsISOJUP (Homo sapiens)6480464CTD[bisphenol A co-treated with Fulvestrant] results in increased methylation of JUP gene; [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of JUP mRNAPMID:28628672 PMID:31601247
Go Back to source page   Continue to Ontology report